Paving a Better Tomorrow Through Science and Technology
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Invited Speakers, International Congress on Science & Technology 2017

Invited Speaker 1

Associate Professor Dr. Huda Abdullah
Department of Electrical, Electronic & Systems Engineering,
Universiti Kebangsaan Malaysia.

Title - From Lab to Market With the Science of Beauty
Amongst the goals of the International Congress on Science and Technology is to provide platform for promoting commercialization of research and getting inspired for, among others, in conducting research with commercial potential so that the outcome of individual research will not end up on the shelf alone. In line to this, we are proud to announce an invited talk presentation by Dr. Huda Abdullah from Universiti Kebangsaan Malaysia on conducting research that is aimed for commercialization of its outcome. Although commercial research by Huda is aimed at selling her research outcome, it is not the only reason for her commercial research activities. She conducts commercial research partially for her admiration of beauty as well as for helping others to look beautiful inside out.

Dr. Huda, the chair person for Nanomaterials and Nanotechnology has been inspired since long ago to channel some of her energy and time conducting research on beauty and break out from traditional research which is mostly for academic break through and advancement. She has successfully formulated in her lab, from scratch, few beauty products using natural ingredients from plants which is 100% safe to use.

We wish Dr. Huda a huge success in her commercial research activities apart from her traditional research. Dr. Huda will distribute limited samples of her product as souvenir during the congress.

Invited Speaker 2

Associate Professor Dr. Gautam Sethi,
Department of Pharmacology,
Yong Loo Lin School of Medicine,
National University of Singapore.

Title - Multifaceted role of gamma tocotrienol in cancer prevention and therapy
Gamma-tocotrienol, a member of Vitamin E superfamily has attracted great attention of late for its anti-proliferative and anti-carcinogenic potential against different cancers. For example, our group has recently reported that anti-proliferative and chemosensitizing effects of g-tocotrienol are associated with its ability to suppress activation of signal transducers and activator of transcription 3 (STAT3), an oncogenic transcription factor that plays a pivotal role in the survival, proliferation, angiogenesis and chemoresistance in diverse malignancies. However, the potential of gamma-tocotrienol to overcome chemoresistance in gastric cancer, which is one of the deadliest cancers in Asia-pacific region, has never been explored before. Hence, we investigated the efficacy of gamma-tocotrienol in combination with capecitabine to modulate tumor growth and survival in xenograft mouse model. Gamma-tocotrienol also inhibited expression of various oncogenic proteins, induced PARP cleavage and inhibited NF-κB activation in gastric cancer cells. In vivo studies using xenograft model of human gastric cancer demonstrated that gamma-tocotrienol alone suppressed tumor growth and this effect was further potentiated in conjunction with capecitabine. As compared to the vehicle control, gamma-tocotrienol further suppressed the NF-κB activation and expression of cyclin D1, COX-2, ICAM-1, MMP-9 and survivin in tumor tissues obtained from treatment groups. Additionally we noted, that gamma tocotrienol can function as a potent inhibitor of angigogenesis in both HUVEC and HCC cells. Overall our results suggest for the first time that gamma-tocotrienol can potentiate the effects of chemotherapy through modulation of multiple biomarkers of proliferation, and angiogenesis in diverse cancers.

About Dr. Gautam Sethi
After completion of his postdoctoral training at University of Texas MD Anderson Cancer Center, Dr. Gautam Sethi joined Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore in 2008 as an Assistant Professor and was promoted to Associate Professor in 2015. The focus of his research over the past few years has been to elucidate the mechanism (s) of activation of oncogenic transcription factors such as NF-kB/STAT3 by carcinogens and inflammatory agents and the identification of novel inhibitors of these proteins for prevention of and therapy for cancer. The findings of his research work have so far resulted in more than two hundred scientific publications in high impact factor peer reviewed journals (with h index = 69) and several international awards. He currently serves as an Academic Editor for PLOS, editorial board member of Scientific Reports, Pharmacological Research, Frontiers in Pharmacology, Frontiers in Oncology, and ad-hoc reviewer for several prestigious international journals.

Invited Speaker 3

Professor Dr. Chong Khim Phin,
Professor for FGV Chair for Sustainable Oil Palm Management,
Universiti Malaysia Sabah.

Title - An Insight into Oil Palm-Ganoderma boninense Interaction: The Way Forward in Managing Basal Stem Rot
Basal Stem Rot caused by Ganoderma boninense is one of the major diseases in oil palm industry in South East Asia. Tremendous efforts have been placed for years in researching and managing the disease, however, with many uncertainties. The pervasiveness of the pathogen and the fact that the economically important of oil palm which prone to infection by G. boninense required an further insight into oil palm-Ganoderma interaction. The competence of the fungi to establish and maintain hemibiotrophic relationship renders the interaction a paramount key on understanding the biology of BSR disease for the development of durable control strategies. The advancement in biotechnology and various ‘omics’ tools have substantively accelerated the research in biological sciences in this area. The recent and ongoing research provides a unique approach to describing these intricate interactions to uncover the mechanisms that take place during the infection. An overview on oil palm-Ganoderma interaction and the establishment of BSR disease are given, drawing together some new fundamental information on pathogenesis and host responses. It is a promising aspect to understand the pathogen and its pathogenesis for future crop improvement, thus constitutes a leap forward to our understanding in plant–pathogen interaction and filling the gap on how to stop the pathogen invasion.

Confirmed Speaker 1

Professor Dr. Tae Kyu An,
Department of Polymer Science & Engineering,
Korea National University of Transportation,
380-702 Chungju,
South Korea.

Title - Repurposing Compact Discs as Master Molds to Fabricate TIPS-Pentacene Nanowire Field-Effect Transistors
Organic field-effect transistors (OFETs) have been developed for several decades due to their potential applications in future electronics such as wearable and foldable electronics. With the progress of their electrical performances, patterning organic semiconducting crystals became a key issue for their real commercialization. However, conventional soft lithographic techniques always needed expensive processes to fabricate high-resolution master molds. In this study, we demonstrate a cost-effective method to prepare nanopatterned master molds to fabricate high-performance nanowire OFETs. We repurposed commercially available compact discs (CDs) as master molds because it possesses linear nanopatterns on their surface. Flexible nanopatterned templates were replicated from the CDs using a UV-imprint lithography. Subsequently, 6,13-bis-(triisopropylsilylethynyl) pentacene nanowires (NWs) were grown from the templates using a capillary force-assisted lithographic technique. The NW-based OFETs showed a high average field-effect mobility of 2.04 cm2 V-1 s-1. It was attributed to the highly crystalline NWs with a crystal orientation favorable for charge transport.

Confirmed Speaker 2

Dr. Taejin Park,
Semiconductor R&D Center,
Samsung Electronics, South Korea.

Title - Control of Sulfur-induced Reduction for Synthesis of Various MoS2 Nanostructures
Transition metal di-chalcogenide (TMDC) is one of the most attractive two-dimensional (2D) materials showing wide-range electrical, optical, mechanical, and chemical properties. Among various TMDCs, atomically thin MoS2 is the most promising semiconducting material applicable to novel electronic and optoelectronic devices because its thickness-dependent bandgap is in a device-applicable range. In addition, the nanostructured MoS2 crystals have a strong potential to be used in hydrogen storages and Li ion batteries due to its abundant electro-chemically active edges. As a result, a huge amount of efforts have been devoted to synthesize a large-scale/few-layered high crystalline MoS2 film as well as various MoS2 nanostructures with high active-site-to-surface-ratio/areal density using a chemical vapor deposition (CVD) method.

Typically, depending on the CVD hardware/process configurations, the MoS2-CVD processes using MoO3 and sulfur precursors can be categorized into two approaches; one uses a gas-phase reaction between weakly reduced volatile MoO3-x and sulfur (one-step mode) and the other uses a solid-state phase transition from intermediate Mo-oxides to MoS2 via sulfur-induced strong reduction (two-step mode). In this work, we used a MoO3-confined substrate structure (confinement of a gas-phase reaction space) and a rapid heating rate (a facile knob to control the strength of sulfur-induced reduction) for the MoS2-CVD process. This unique hardware/process set-up enabled formation of various MoS2 features such as various 2D planar films (with triangle, star, and dendrite shapes) and 3D nanostructures (vertically standing crystals). Various features of the CVD-grown MoS2 were examined using secondary electron microscopy and scanning transmission electron microscopy, and the detailed MoS2-CVD mechanism was suggested. We expect that our findings on the synthetic mechanism of the various MoS2 features can contribute to realization of various futuristic MoS2-based devices.

The Organizer of ICST 2017.
Organizer of ICST 2017